The short answer
Almost all shoulder pain is rotator cuff, impingement or arthritis. Pain not reproduced by moving the shoulder, with no injury, night waking and hand or eye signs, needs chest imaging.
Rotator cuff problems, impingement, frozen shoulder, arthritis and referred neck pain account for nearly all shoulder pain.
Mechanical pain is reproduced by movement, tender to press, and improves over weeks with rest and physiotherapy.
Referred pain follows different rules: diaphragm irritation causes shoulder-tip pain, and cardiac pain comes with chest and breathing symptoms.
NCI describes a Pancoast (superior sulcus) tumor as a non-small cell lung cancer that begins in the upper part of the lung and can spread to nearby tissues such as the chest wall, large blood vessels and spine.
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The whole article, with every detail and caution.
This page is for people with shoulder pain that has no clear injury behind it or is not getting better. It covers when to get help, the usual causes, and the rare pattern that can point to a tumor at the top of the lung.
How long is too long to wait
Seek emergency care now for shoulder or arm pain with chest tightness, sweating, nausea, or breathlessness. Also seek emergency care for shoulder-tip pain with severe abdominal pain, dizziness, or fainting.
Book an appointment sooner if any of these apply.
- There was no injury at all.
- The pain wakes you consistently at night.
- It is getting worse each week rather than settling.
- Any of the neurological or eye features below have appeared.
Pain that followed a clear strain, and that changes with position and movement, is often managed with activity changes and physiotherapy (physical therapy), with a check-in after four to six weeks. Ask your care team what fits your situation. If you have already had six weeks of treatment with no improvement, ask specifically whether imaging should include the chest, not only the shoulder.
What shoulder pain usually turns out to be
The overwhelming majority of shoulder pain is mechanical. Nearly all of it comes from a short list:
- rotator cuff tendinopathy (tendon damage) and tears
- subacromial impingement (tendons pinched under the top of the shoulder blade)
- adhesive capsulitis (frozen shoulder)
- osteoarthritis
- pain referred from an arthritic neck
These share a recognizable pattern. The pain links to particular movements or positions. A clinician can reproduce it by moving your arm. It is often tender to press. It tends to improve over weeks with rest, activity changes, and physiotherapy.
Cancer is an uncommon cause of shoulder pain. It appears on this list because when it does cause shoulder pain, the pain behaves differently. That difference is learnable.
Pain that is referred rather than local
Structures that have nothing to do with the shoulder joint can send pain there.
The diaphragm shares nerve supply with the skin over the tip of the shoulder. So irritation beneath it can cause shoulder pain with an entirely normal shoulder exam. This includes irritation from the liver, gallbladder, spleen, an abscess, or the lining of the lung. Heart problems refer pain to the left shoulder and arm, usually with chest heaviness, sweating, or breathlessness.
The pattern most relevant here comes from the very top of the lung. Tumors in that position are known as Pancoast or superior sulcus tumors. NCI describes them as non-small cell lung cancer that begins in the upper part of the lung and can spread to nearby tissues such as the chest wall, large blood vessels and spine. NCI also notes that lung cancer sometimes causes no signs or symptoms, and lists a cough that gets worse, breathing trouble, chest pain, hoarseness, unexplained weight loss and fatigue among the common warning signs. Because shoulder pain from a tumor can look like a joint problem, tell your clinician if the pain does not behave like an injury.
The features that separate it from an injury
Consider raising these specifically if they apply to you.
- No injury, strain, or unaccustomed activity preceded the pain.
- The pain is not reproduced by moving the shoulder, and moving it freely does not make it worse.
- Pain wakes you at night and does not settle whatever position you take.
- The pain is steadily worsening over weeks rather than fluctuating.
- Six weeks of physiotherapy or rest have produced no change at all.
- Numbness, tingling or weakness in the hand on the same side.
- A change in an eye or eyelid on the same side as the pain.
- Hoarseness, breathlessness, a cough that is getting worse, or unexplained weight loss.
Any of these together with shoulder pain is a reason to see a clinician promptly.
What a workup involves
A thorough assessment examines the shoulder, the neck, and the chest. It includes a neurological exam of the arm and hand. Reproducing the pain with shoulder movement points strongly toward a joint or tendon cause. Being unable to reproduce it is itself informative.
Which tests are used depends on your history and examination, and your clinician decides. If there was no injury, it is reasonable to ask whether imaging should include the chest, not only the shoulder.
Sources

Common questions
How do I tell mechanical shoulder pain from referred pain?
Mechanical pain has a movement signature: certain arcs hurt, pressing on the area hurts, and position changes it. Referred pain is largely unaffected by how you move your arm, and a clinician often cannot reproduce it during examination.
Is night pain always a red flag?
No. Rotator cuff problems and frozen shoulder commonly hurt at night, particularly when lying on that side. What is different is pain that wakes you regardless of position, does not ease when you shift, and is getting worse week by week.
I have had physiotherapy for six weeks with no change. What next?
That is a reasonable point to reassess rather than continue. Ask specifically whether the assessment has included your neck, your hand strength and sensation, and whether chest imaging is warranted given there was no injury.
Will a shoulder X-ray or MRI find a lung tumor?
Not necessarily. A shoulder X-ray or MRI is aimed at the shoulder, not the lung. If there was no injury and the pain is not improving, ask your clinician whether imaging of the chest is appropriate.
I have never smoked. Does that rule it out?
No. NCI notes that many people with risk factors never develop lung cancer, whereas others with no known risk factors do, and that people who have never smoked can develop lung cancer. If pain is not behaving like an injury, tell your clinician.
Questions to ask your doctor
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Written by: Cancer ExplainedSources last checked: 2026-10-16 what this meansLast updated: 2026-10-16Next planned review: 2027-08-03
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How this page was created
Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Source checked — This page was written with AI assistance and then compared with the sources listed on it, looking for statements those sources do not back up. That check is not a sentence-by-sentence record and can miss errors. It is not a medical review, and it does not confirm the page is complete or right for your situation.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
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