The short answer
A neoplasm is an abnormal mass of tissue. It is another word for tumor. NCI says a neoplasm may be benign, which is not cancer, or malignant, which is cancer. The word alone does not tell you which.
Neoplasm means an abnormal mass of tissue. It is another word for tumor.
A neoplasm may be benign (not cancer) or malignant (cancer).
Look for the word next to it, such as benign neoplasm or malignant neoplasm.
NCI lists neoplasm as a common term on cancer pathology reports.
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This page is for people who see the word neoplasm on a pathology report, a scan report or a patient portal. It explains the word and what to look for next to it.
The short answer
Neoplasm is another word for tumor. NCI defines it as an abnormal mass of tissue that forms when cells grow and divide more than they should, or do not die when they should.
NCI says a neoplasm may be benign or malignant. Benign means not cancer. Malignant means cancer. So the word neoplasm on its own does not tell you whether you have cancer.
Look at the word beside it
Reports often put a describing word next to neoplasm.
- Benign neoplasm. NCI says benign neoplasms may grow large but do not spread into, or invade, nearby tissues or other parts of the body.
- Malignant neoplasm. NCI says malignant neoplasms can spread into, or invade, nearby tissues. They can also spread to other parts of the body through the blood and lymph systems.
If your report says only "neoplasm" with no other word, ask your care team which one it is. Ask also whether the report is final or whether more testing is still needed.
Where you may see it
NCI lists neoplasm among the common terms on a cancer pathology report. The same list includes benign, malignant, carcinoma, invasive, in situ, and margin. NCI says the diagnosis section of a pathology report is the pathologist's summary of the findings. It is where the cancer type is named, along with the tumor grade, lymph node status, margin status and stage.
The word is also part of some cancer names. NCI defines a plasma cell neoplasm as a type of tumor that begins in plasma cells. It lists multiple myeloma as one type.
Related words
- Neoplasia is NCI's word for abnormal and uncontrolled cell growth.
- Mass is a lump in the body. NCI says a mass may be benign or malignant.
- Lesion is an area of abnormal or damaged tissue. NCI says a lesion may be benign or malignant.
These pages explain wording that often appears with neoplasm: benign versus malignant, solid mass, and how to read a pathology report.
Benign does not always mean harmless
NCI says benign tumors usually do not grow back when removed, whereas cancerous tumors sometimes do. It also says benign tumors can sometimes be quite large, and that some can cause serious symptoms or be life threatening, such as benign tumors in the brain. Your care team can tell you whether yours needs treatment or watching.
Is this urgent?
The word neoplasm is not an emergency by itself. Ask your care team when the rest of your results will be ready and what comes next. If you have new or worsening symptoms while you wait, call your care team right away. If you think you are having an emergency, call 911.
What to ask your team
- Is my neoplasm benign or malignant?
- What type of cells is it made of?
- Does it need treatment, or will it be watched?
- What is the next step, and when will I hear about it?
Sources

Common questions
What is a neoplasm?
NCI defines a neoplasm as an abnormal mass of tissue that forms when cells grow and divide more than they should or do not die when they should. NCI says neoplasm is also called a tumor.
Does neoplasm mean cancer?
Not by itself. NCI says neoplasms may be benign (not cancer) or malignant (cancer). A malignant neoplasm is cancer. A benign neoplasm is not.
What is the difference between a benign and a malignant neoplasm?
NCI says benign neoplasms may grow large but do not spread into, or invade, nearby tissues or other parts of the body. Malignant neoplasms can invade nearby tissues. They can also spread to other parts of the body through the blood and lymph systems.
What does neoplasia mean?
NCI defines neoplasia as abnormal and uncontrolled cell growth.
Can a benign neoplasm still cause problems?
NCI says benign tumors can sometimes be quite large, and that some can cause serious symptoms or be life threatening, such as benign tumors in the brain. Ask your care team what your result means for you.
Questions to ask your doctor
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More words from this kind of report
Other guides in biopsy & pathology reports.
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Written by: Cancer ExplainedSources last checked: 2026-10-19 what this meansLast updated: 2026-10-19Next planned review: 2027-10-19
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How this page was created
Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Source checked — This page was written with AI assistance and then compared with the sources listed on it, looking for statements those sources do not back up. That check is not a sentence-by-sentence record and can miss errors. It is not a medical review, and it does not confirm the page is complete or right for your situation.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
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