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Acrylamide in chips and fries: what FDA says about the risk

Acrylamide forms when starchy foods are cooked at high heat. FDA says it caused cancer in animals at very high doses, and advises a healthy eating pattern rather than avoiding these foods.

Source

NCI last reviewed source: 2024-03-05

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Key fact

Acrylamide forms from sugars and the amino acid asparagine during high-temperature cooking.

The short answer

Acrylamide forms in some foods during high-temperature cooking such as frying, roasting and baking. FDA says it caused cancer in animals given very high doses. FDA does not tell people to stop eating fried, roasted or baked foods; it advises following a healthy eating plan and offers cooking tips that lower how much forms.

  • Acrylamide forms from sugars and the amino acid asparagine during high-temperature cooking.

  • It shows up mainly in plant-based foods, especially potato products, grain products and coffee.

  • It does not form, or forms at lower levels, in dairy, meat and fish products.

  • FDA says acrylamide caused cancer in animals in studies using very high doses.

Choose how you want to understand this

The full explanation.

Where this chemical comes from.

Acrylamide is not an additive. Nobody puts it in your food on purpose. FDA describes it as a chemical that can form in some foods during high-heat cooking, like frying, roasting, and baking.

The reaction itself is ordinary kitchen chemistry. Acrylamide forms from sugars and an amino acid called asparagine, when food gets cooked at high heat. It is part of the same browning that gives fried potatoes their color and taste.

That fact tells you which foods are affected. Plant-based foods react most, especially potato products, grain products, and coffee. FDA notes that acrylamide does not form, or forms at lower levels, in dairy, meat, and fish products.

What the animal studies showed.

FDA's summary of the science is careful, and that care matters. Acrylamide caused cancer in animals, but only in studies where the animals got very high doses.

Two parts of that sentence carry weight. The finding was in animals. The doses were very high.

Neither point makes the finding meaningless. Animal studies act as an early warning system. But a result from very high lab doses does not automatically mean risk at the amounts people actually eat. FDA does not treat it that way either.

What is known about people.

FDA notes that in 2010, a joint expert panel from the FAO and WHO said acrylamide is a human health concern. They called for more long-term studies. That is a request for more research — a sign the human picture was not settled at the time.

NCI states the human evidence more directly. Its acrylamide fact sheet says a large number of studies in humans have found no consistent evidence that dietary acrylamide exposure is associated with the risk of any type of cancer.

A hazard shown in animals. An official call for more research. No steady link found in humans. Holding all three facts at once is the accurate picture.

FDA's actual advice.

For a topic that generates scary headlines, FDA stays remarkably calm. Its advice is simple: follow a healthy eating plan that matches the Dietary Guidelines for Americans. That means more fruits, vegetables, and whole grains, and less saturated fat and sodium.

FDA does not tell people to avoid fried, roasted, or baked foods altogether.

Cooking and storage tips that lower formation.

Want to cut down how much acrylamide forms? FDA's page on acrylamide and diet, food storage and food preparation gives clear, easy steps.

  • Comparing frying, roasting and baking potatoes, frying causes the highest acrylamide formation.
  • Boiling potatoes, and microwaving whole potatoes with the skin on, does not produce acrylamide.
  • Soaking raw potato slices in water for 15 to 30 minutes before frying or roasting helps reduce formation. Drain and blot them dry before cooking so they do not spit.
  • Cook cut potato products to a golden yellow color rather than a brown color. Brown areas tend to contain more acrylamide.
  • Toast bread to a light brown color rather than a dark brown color.
  • Store potatoes outside the refrigerator, preferably in a dark, cool place such as a closet or a pantry. Refrigerating them can result in increased acrylamide during cooking.

That last tip about potato storage is the one most people have never heard. It costs nothing to try.

Keeping this in proportion.

Fried potato products already have good reasons to eat in moderation, and none of them are about acrylamide. If chips and fries make up a big part of your diet, your overall eating pattern is the thing worth looking at.

If they are just an occasional treat, FDA's guidance gives you no reason to cut them out. Cook them golden instead of dark, keep your potatoes out of the fridge, and save your worry for something that matters more.

Other foods on the list.

Potatoes and coffee get most of the attention, but acrylamide can form in other browned foods too. Toast, crackers, breakfast cereals, and roasted nuts all go through the same basic browning reaction at high heat. The same rule applies across all of them: less browning generally means less acrylamide.

This is not a reason to give up toast. It is simply useful background for understanding why FDA's advice is about an overall eating pattern rather than a single food to avoid.

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Common questions

Do I need to stop eating potato chips and fries?

FDA does not say that. Its advice is to adopt a healthy eating plan consistent with the Dietary Guidelines for Americans rather than avoiding fried, roasted or baked foods altogether.

What actually happens when the food browns?

Acrylamide forms from sugars and an amino acid called asparagine during certain types of high-temperature cooking. The browner the surface, the more has formed, which is why FDA suggests cooking to golden yellow rather than brown.

How should I store potatoes?

FDA advises storing potatoes outside the refrigerator, because refrigerating them can result in increased acrylamide during cooking. It suggests a dark, cool place such as a closet or a pantry.

Is there a way to cook potatoes with none of it?

FDA says boiling potatoes and microwaving whole potatoes with the skin on does not produce acrylamide, while among frying, roasting and baking, frying causes the highest formation.

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Sources last checked: 2026-08-11 what this meansLast updated: 2026-08-11Next planned review: 2027-08-11

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How this page was created

Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes. We do not employ clinicians and do not intend to — our work is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.

Editorial status: Source checked This page was written with AI assistance and checked line by line against the sources listed on it. That confirms the sources support what the page says. It is not a medical review, and it does not confirm the page is complete or right for your situation.

Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.

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