The short answer
A hiccup is a spasm of the diaphragm followed by a snap of the vocal cords. Several triggers listed by MedlinePlus overlap with cancer care, including abdominal surgery and nerve irritation, and often no cause is found. If hiccups run past a few days, that is the point to contact a provider.
MedlinePlus defines a hiccup as an unintentional spasm of the diaphragm, the muscle at the base of the lungs.
Listed triggers include abdominal surgery, nerve irritation from conditions such as pneumonia or pleurisy, stroke and brain tumors.
MedlinePlus notes that often no cause can be identified.
Home measures named are breathing into a paper bag, drinking cold water, a teaspoon of sugar, and holding your breath.
Choose how you want to understand this
The full explanation.
What a hiccup actually is
MedlinePlus describes a hiccup as an unintentional movement, a spasm, of the diaphragm. The diaphragm is the sheet of muscle at the base of your lungs that drives your breathing.
The muscle contracts suddenly. Your vocal cords snap shut right after. That closure is what makes the noise.
Once a day at dinner, this is a joke. Once every few seconds for two days, it stops being funny. It interferes with eating, with talking and with sleep, and people going through cancer treatment have limited reserves for that kind of interruption.
What sets them off
The triggers MedlinePlus lists are a mixed bag:
- Hot and spicy foods or liquids
- Abdominal surgery
- Nerve irritation, from conditions such as pneumonia or pleurisy
- Harmful fumes
- Stroke or brain tumors
- Often, no cause that anyone can identify
Three of those overlap with a cancer journey in obvious ways. Abdominal surgery is on the list. So is nerve irritation from lung inflammation. So are brain tumors.
Worth being straight about: the MedlinePlus page does not name chemotherapy drugs or steroid medicines as causes of hiccups. Plenty of people in treatment report them, and your own oncology team may well have seen a pattern with a specific drug. But we are not going to put a claim in writing that our source does not make. Ask your team directly, because they know your regimen.
The home remedies
MedlinePlus lists four self-help approaches that may bring relief:
- Breathing into a paper bag
- Drinking cold water
- Swallowing a teaspoon of sugar
- Holding your breath
There is no ranking, and no promise attached. They are cheap and quick, which is most of their appeal. If one works for you, use it.
If you are on a fluid restriction, a modified diet, or recovering from surgery on your mouth, throat or abdomen, check with your team before swallowing sugar or gulping cold water. What is harmless for most people is not automatically harmless for you right now.
When home measures stop being the answer
MedlinePlus draws the line clearly: contact a healthcare provider if hiccups go on for more than a few days.
That is a reasonable trigger to phone in. Hiccups that have run for days are wearing you down, and they may also be pointing at something worth investigating, given that nerve irritation and other conditions are on the cause list.
What clinicians can try
For hiccups that will not quit, MedlinePlus lists several options providers may turn to:
- Gastric lavage, which means washing out the stomach
- Carotid sinus massage, which is done only by a provider and never by you at home
- Medications
- Nasogastric intubation, a thin tube passed through the nose into the stomach
- A phrenic nerve block, used in rare cases
That last one targets the nerve that runs the diaphragm. It is at the far end of the list for a reason.
The useful takeaway is that persistent hiccups are treatable. People sometimes suffer through them for weeks because they assume nothing can be done, or because it feels like too trivial a thing to raise when your team is dealing with your cancer. It is not trivial if it is stopping you eating and sleeping, and there are things to try.
What to bring to the appointment
Note when they started, roughly how long each bout lasts, whether anything makes them better or worse, and what they are costing you. If they are keeping you from finishing meals or from sleeping through the night, say so in those words. That is the detail that moves hiccups from a footnote to something your team acts on.
Words to know
Tap any term to see what it means.

Common questions
Is it true that chemotherapy or steroids cause hiccups?
The MedlinePlus page on hiccups does not name chemotherapy drugs or steroids among its causes, so we are not going to claim it does. It does list abdominal surgery, nerve irritation, stroke and brain tumors, and it says a cause often cannot be found. Ask your own team whether anything in your regimen is known for this.
How long is too long?
MedlinePlus says to contact a healthcare provider if hiccups go on for more than a few days. That is the line it draws.
What can a doctor actually do about them?
For hiccups that persist beyond a few days, MedlinePlus lists gastric lavage, carotid sinus massage performed only by a provider, medications, nasogastric intubation, and in rare cases a phrenic nerve block.
Do the folk remedies work?
MedlinePlus lists breathing into a paper bag, drinking cold water, swallowing a teaspoon of sugar and holding your breath as things that may provide relief. It does not promise they will work.
Questions to ask your doctor
Being prepared helps you get the most out of your appointments. Save or print these questions.
Tap a question to save it to your list (kept on this device).
Your next step
Turn this topic into questions for your next appointment.
Speak With Trained Specialists & Human Navigators
Cancer Explained provides educational guidance, but does not replace trained specialists, social workers, or your medical team.
Talk to a trained cancer information specialist
Free, confidential assistance from NCI Cancer Information Service via phone, chat, or email.
Contact your oncology team
Locate after-hours contact numbers, portal messages, or urgent triage phone lines.
Find a patient navigator
Get one-on-one help with appointments, logistics, translation, and care coordination.
Find a genetic counselor
Discuss inherited mutation risk, family history, and genetic testing options.
Find an oncology social worker
Access emotional counseling, family support groups, and mental health resources.
Find a financial navigator
Locate copay assistance foundations, grant programs, and lodging/travel support.
Find a clinical-trial specialist
Search matching studies and speak with NCI trial information specialists.
Get urgent help
Immediate emergency guidance for fever (>100.4°F during chemo), severe pain, or shortness of breath.
Help Us Improve This Guide
Did this explanation answer your question and help you determine your next step?
Know someone who needs this?
Plenty of people are looking for something like this and do not know where to start. If this would help a friend or someone you love, send it on — we have written an opening line so you do not have to stare at an empty message. You can change every word of it.
Your message is written and sent in your own email or messaging app — we never see who you send it to, and nothing is added to any list.
Plain-language explanation of the published sources cited on this page. AI-assisted, source-checked, not clinician-reviewed.
Sources last checked: 2026-08-11 what this meansLast updated: 2026-08-11Next planned review: 2027-08-11
How this page was created
Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes. We do not employ clinicians and do not intend to — our work is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status — Source checked. This page was written with AI assistance and checked line by line against the sources listed on it. That confirms the sources support what the page says. It is not a medical review, and it does not confirm the page is complete or right for your situation.
General education — varies by person. Answers genuinely differ between people. This page explains what commonly varies and points you to your care team for your situation.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
How this page was created
Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes. We do not employ clinicians and do not intend to — our work is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Source checked — This page was written with AI assistance and checked line by line against the sources listed on it. That confirms the sources support what the page says. It is not a medical review, and it does not confirm the page is complete or right for your situation.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
Read more about our editorial process, our use of AI, and our corrections policy.
Spotted a problem? Report an error — a factual mistake, broken or outdated source, confusing wording, or anything that seems unsafe. Please do not include names, medical record numbers, dates of birth, addresses, or other identifying medical information in your report.
After using this page, do you understand what to do next?
Anonymous — we only record the answer, never who gave it.
Related articles
Still have questions?
Educational answers, plain language
Free to print and share
