The short answer
Which help you can get depends on your insurance. Copay cards suit commercial plans, charitable funds cover people on Medicare, and manufacturer programs give free drug to the uninsured.
Manufacturer copay cards usually cannot be used by anyone on Medicare, Medicaid or TRICARE — for those plans, charitable copay funds are the route.
TotalAssist, the merged Patient Advocate Foundation and PAN Foundation program launched 1 July 2026, covers copays, coinsurance, deductibles and insurance premiums: 866-512-3861, 8:30am-5:30pm ET.
HealthWell Foundation, (800) 675-8416, requires insurance, an open disease fund, income within 500% of the federal poverty level, and treatment in the US.
CancerCare Co-Payment Assistance Foundation, 866-55-COPAY (866-552-6729), covers chemotherapy and targeted-therapy copays only, not scans, radiation or labs.
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The full explanation.
First, find out which kind of help you are eligible for
Almost every mistake here comes from applying to the wrong sort of program. What you can use depends on what insurance you have.
- No insurance at all — manufacturer patient assistance programs, which can supply the drug free.
- Commercial or employer insurance — manufacturer copay cards, which pay down your share at the pharmacy.
- Medicare, Medicaid, TRICARE or VA — copay cards are generally not available to you. Independent charitable foundations are the route instead, plus Medicare Extra Help.
Say your insurance type in the first sentence of every call. It saves an hour.
Manufacturer programs
Nearly every company that makes a cancer drug runs a patient assistance program that provides the medicine at no or reduced cost to people who meet income and insurance rules, and a separate copay card for people with commercial insurance.
Find the one for your specific drug through the Medicine Assistance Tool at medicineassistancetool.org, or through two free directories the National Cancer Institute points to: NeedyMeds, which lists programs that help pay for medicines and supplies, and RxAssist, a directory of drug company assistance programs. Your oncology pharmacist can usually name the program for your drug from memory.
Copay cards have a maximum annual benefit, and some insurers no longer count that money toward your deductible. Ask your plan whether copay assistance counts toward your out-of-pocket maximum before you rely on it.
Charitable copay foundations, by name
These are independent charities. They run disease-specific funds that open and close as money comes in, and most people on Medicare use them.
TotalAssist. Patient Advocate Foundation and PAN Foundation merged, and launched TotalAssist on 1 July 2026 as a single program covering nearly 150 serious and chronic conditions. Grants can go toward medication copays, coinsurance and deductibles, health insurance premiums, office visit charges on the day of treatment, and treatment administration charges. Call 866-512-3861, Monday to Friday 8:30 a.m. to 5:30 p.m. ET; press 2 for Spanish. Patient Advocate Foundation's main line for case management is (800) 532-5274.
HealthWell Foundation. Covers coinsurance, copays, deductibles, health insurance premiums and other out-of-pocket costs. To qualify you must have some form of health insurance, have a disease with an open fund, have income within 500% of the federal poverty level, and be treated in the US or a US territory. Call (800) 675-8416, Monday to Friday 9 a.m. to 5 p.m. ET.
CancerCare Co-Payment Assistance Foundation. Covers copayment, coinsurance and deductibles for chemotherapy or targeted treatment medications only — not scans, radiation or lab work. You must be insured, and a US citizen or legal resident; adjusted gross income up to five times the federal poverty level may qualify. Call 866-55-COPAY (866-552-6729), Monday to Thursday 9 a.m. to 7 p.m. ET, Friday until 5 p.m. CancerCare's general line is 800-813-HOPE (4673).
Blood Cancer United, formerly the Leukemia & Lymphoma Society, runs a Co-Pay Assistance Program covering insurance premiums and treatment-related copays and coinsurance for prescription drugs, labs, scans and tests. Information Specialists: (800) 955-4572; the Patient Financial Assistance team: (877) 557-2672.
Funds close. When one does, ask to be added to its notification list and apply the moment it reopens. Reapply every January, because grants run by calendar year.
If you are on Medicare
Extra Help, the Part D Low-Income Subsidy, is the single biggest lever. Medicare.gov's 2026 figures: qualify with income up to $23,940 for an individual or $32,460 for a married couple, and resources up to $18,090 or $36,100. With it you pay a $0 premium, a $0 deductible, no more than $5.10 for a generic and $12.65 for a brand-name drug, and $0 once your total drug costs reach $2,100.
Apply free through Social Security at 1-800-772-1213 (TTY 1-800-325-0778), weekdays 8 a.m. to 7 p.m. local time.
Lower-cost routes worth asking about
- Rx Outreach, a nonprofit mail-order pharmacy, 1-888-796-1234.
- Discount card prices such as GoodRx, which sometimes beat your copay on generics. You cannot combine a discount card with insurance on the same fill, so ask the pharmacist to price both ways.
- Your hospital's own assistance. Many cancer centers have charity care policies and 340B pricing. Ask the financial counselor for the written policy, not a verbal answer.
- The Cancer Financial Assistance Coalition database at cancerfac.org, searchable by diagnosis, ZIP code and type of help.
- NCI's Cancer Information Service, 1-800-4-CANCER (1-800-422-6237).
Two things not to do
Do not skip or stretch doses to save money without telling your oncology team — say the words "I cannot afford this" and let them find a covered alternative. And do not pay a large surprise pharmacy bill before someone has checked whether a foundation, a manufacturer program or an appeal applies.
This page is educational and is not financial, insurance or benefits advice. Program rules change; confirm current terms with each organization before you rely on them.
Sources
- National Cancer Institute — Managing Cancer Costs and Medical Information
- Medicare — Help with drug costs (Extra Help / Part D Low-Income Subsidy)
- Social Security Administration — Medicare Part D Extra Help
- HealthWell Foundation — Eligibility and disease funds
- CancerCare Co-Payment Assistance Foundation
- Cancer Financial Assistance Coalition — Searchable resource database
Words to know
Tap any term to see what it means.

Common questions
What help exists for expensive cancer drugs?
Several kinds may help: patient assistance programs run by drug makers, copay assistance programs, grants from cancer nonprofits, and prescription discount options. What you qualify for depends on the drug, your income, and your insurance.
What is a patient assistance program?
Many drug companies offer patient assistance programs that provide medicines at low or no cost to people who meet income and insurance rules. Your care team or pharmacist can help you check and apply.
What is copay assistance?
Copay assistance helps cover the part of a drug's cost you pay yourself. It may come from drug makers or nonprofit foundations, and rules vary by program and insurance type.
Who can help me apply?
A hospital social worker, financial counselor, oncology pharmacist, or patient navigator can help you find programs and complete applications. Ask your care team early.
Questions to ask your doctor
Being prepared helps you get the most out of your appointments. Save or print these questions.
Tap a question to save it to your list (kept on this device).
Your next step
Your care team's answer depends on your treatment — ask them directly.
Speak With Trained Specialists & Human Navigators
Cancer Explained provides educational guidance, but does not replace trained specialists, social workers, or your medical team.
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Free, confidential assistance from NCI Cancer Information Service via phone, chat, or email.
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Find a patient navigator
Get one-on-one help with appointments, logistics, translation, and care coordination.
Find a genetic counselor
Discuss inherited mutation risk, family history, and genetic testing options.
Find an oncology social worker
Access emotional counseling, family support groups, and mental health resources.
Find a financial navigator
Locate copay assistance foundations, grant programs, and lodging/travel support.
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Search matching studies and speak with NCI trial information specialists.
Get urgent help
Immediate emergency guidance for fever (>100.4°F during chemo), severe pain, or shortness of breath.
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Where to get help with this, by name
A hospital social worker or financial navigator is the best first call if you have one. If you do not, these organisations help at no cost to you.
- Patient Advocate Foundation — (800) 532-5274. Case managers take on insurance appeals, denials and medical debt with you. Free.
- TotalAssist (Patient Advocate Foundation's copay programme, merged with the PAN Foundation in 2026) — 866-512-3861. Help with medication copays, coinsurance and deductibles, insurance premiums, and office-visit and administration charges on the day of treatment, across nearly 150 conditions.
- CancerCare — 800-813-HOPE (4673). Oncology social workers, free counselling and support groups. Limited financial help with transport, home care, child care and lodging for people in active treatment who meet their income guidelines — funding is first-come, first-served, so call to ask what is open.
- Triage Cancer — 424-258-4628. Free legal and financial navigation: insurance, employment rights, disability.
- Blood Cancer United (formerly the Leukemia & Lymphoma Society) — (800) 955-4572. Information Specialists answer questions on treatment, insurance and financial problems.
- HealthCare.gov — 1-800-318-2596. For questions about the external review process — the independent review your insurer is required by law to accept.
Your state Department of Insurance regulates insurers and takes consumer complaints. On Medicare, your State Health Insurance Assistance Program (SHIP) gives free one-to-one counselling. If a specific drug is the problem, ask the manufacturer about its patient assistance programme.
Phone numbers checked 31 July 2026. Programmes and eligibility change — if a number has moved, please tell us.
Plain-language explanation of the published sources cited on this page. AI-assisted, source-checked, not clinician-reviewed.
Sources last checked: 2026-07-31 what this meansLast updated: 2026-08-11Next planned review: 2027-01-31
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Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes. We do not employ clinicians and do not intend to — our work is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
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Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
How this page was created
Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes. We do not employ clinicians and do not intend to — our work is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Source checked — This page was written with AI assistance and checked line by line against the sources listed on it. That confirms the sources support what the page says. It is not a medical review, and it does not confirm the page is complete or right for your situation.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
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