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Brain Tumor Treatment Options

A plain-language overview of the main treatments for brain tumors — surgery, radiation, and chemotherapy — and how the plan is chosen.

NCI source:National Cancer Institute - Adult Central Nervous System Tumors Treatment (PDQ®)–Patient Version

Review status: AI-assisted, source checked. Not reviewed by a clinician. How we check pages

The short answer

Brain tumor treatment depends on the type, grade, and location of the tumor. Surgery to remove as much as safely possible is often the first step, followed by radiation therapy and sometimes chemotherapy. Treatment aims to control the tumor while protecting brain function.

  • Treatment depends on the tumor's type, grade, and location.

  • Surgery to remove as much of the tumor as safely possible is often the first step.

  • Radiation therapy is commonly used, sometimes after surgery.

  • Chemotherapy or other drug therapies may be used for certain tumors.

Choose how you want to read this

The whole article, with every detail and caution.

This page is for adults facing a brain or spinal cord tumor, and the people helping them. It explains how a treatment plan is built and the main options: surgery, radiation, and drug treatment.

How the plan gets built

Brain tumor treatment depends on the specific type of tumor, its grade, and where it sits. It also depends on your age and overall health. Your team builds a plan around your specific tumor, not the general category.

Surgery: removing as much as safely possible

Surgery to remove the tumor is one of the standard treatments. Surgeons aim to remove as much tumor as possible while protecting the brain function around it. How much can safely come out depends on where the tumor sits. Sometimes a needle biopsy is used instead of open surgery.

For slow-growing tumors, the National Cancer Institute notes that active surveillance may be used. This means closely watching your condition and not giving treatment unless there are changes. After surgery removes all the cancer that can be seen, some patients are given chemotherapy or radiation to kill any cancer cells that are left.

Radiation: precise or broad, depending on the goal

Radiation therapy uses high-energy rays to kill tumor cells. It may be given after surgery to kill cells that are left. There are two main kinds:

  • Stereotactic radiosurgery is typically given in one dose, or up to five doses once a day, according to the NCI.
  • External beam radiation is most often given once a day, five days a week.

Your team will explain which kind, if any, fits your tumor.

Chemotherapy and drug treatment

The National Cancer Institute lists several drugs used for central nervous system tumors, including:

  • Temozolomide, a chemotherapy drug.
  • Carmustine, which can also be given as an implant placed at the surgery site.
  • Bevacizumab, a targeted therapy drug.

Another approach is tumor treating fields. The FDA has approved a wearable device that delivers alternating electric fields to the head. It is approved for use with temozolomide in adults with newly diagnosed glioblastoma after surgery and radiation.

Why the tumor's grade changes the whole approach

Grade describes how fast a tumor is likely to grow. The NCI describes grade I tumors as slow growing and grade IV tumors as growing and spreading very quickly. Your team uses grade, type, and location to plan treatment. Ask what the goals of treatment are for your tumor.

Spinal cord tumors

For tumors in the spinal cord, the NCI lists surgery to remove the tumor as one option. Your team will explain the trade-offs for you.

What to ask your team

  • What is my tumor's exact type and grade, and how does that shape my treatment plan?
  • How much of the tumor can be safely removed with surgery?
  • Will I need radiation, chemotherapy, or both in addition to surgery?
  • Has my tumor been tested for molecular markers such as IDH mutation or MGMT methylation, and does that change my options?
  • Is a clinical trial a reasonable option for me?

Sources

Microscope view of pink and purple stained tissue with swirling cell patterns.
Stained tissue slide at low magnificationMikael Häggström, M.D., via Wikimedia Commons (CC0)

Common questions

What are the main treatments?

The main treatments are surgery, radiation therapy, and chemotherapy or other drug therapies. The combination depends on the tumor's type, grade, and location.

What does surgery do?

Surgery aims to remove as much of the tumor as safely possible without harming important brain functions. It also provides a tissue sample to confirm the type and grade. Sometimes a tumor cannot be fully removed because of its location.

When is radiation used?

Radiation therapy uses high-energy rays to kill tumor cells. It may be given after surgery to kill any cells that are left.

Is chemotherapy used for brain tumors?

Chemotherapy or other drug therapies are used for certain brain tumors, often alongside surgery and radiation. The choice depends on the specific tumor type.

How is the plan chosen?

The care team weighs the tumor's type, grade, and location against the goal of protecting brain function, along with the person's overall health and wishes.

Questions to ask your doctor

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Prepared by Cancer Explained's AI-assisted editorial system

Written from National Cancer Institute material and compared with the source cited below.

Plain-language explanation of the published sources cited on this page. AI-assisted, source-checked, not clinician-reviewed.

Last updated: 2026-10-16Next planned review: 2027-07-07

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How this page was created

Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.

Editorial status: Source checked — This page was written with AI assistance and then compared with the sources listed on it, looking for statements those sources do not back up. That check is not a sentence-by-sentence record and can miss errors. It is not a medical review, and it does not confirm the page is complete or right for your situation.

Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.

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