The short answer
American Indian and Alaska Native communities face certain cancer disparities, including the highest liver and bile duct cancer rates and higher kidney cancer death rates than other groups. NCI links cancer disparities to social conditions and access to care. Talk with your provider about screening.
American Indians and Alaska Natives have the highest liver and bile duct cancer rates of any group.
They also have higher kidney cancer death rates than any other racial or ethnic group.
They have higher cervical cancer rates than several other groups.
NCI links cancer disparities to social conditions and access to care.
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The whole article, with every detail and caution.
This page is for American Indian and Alaska Native people and their families, and anyone who wants to understand cancer gaps in these communities. It covers the key patterns, why they exist, and steps that can help.
The simple version
American Indian and Alaska Native communities include many distinct nations and cultures. Like other groups, they face certain cancer disparities, differences in how cancer affects them.
Several patterns stand out in NCI's data, including the highest liver and bile duct cancer rates and higher kidney cancer death rates than other groups. NCI links cancer disparities to social conditions and access to care.
These communities face real cancer gaps, linked to social conditions and access to care.
The patterns to know
NCI's data point to a few specific concerns for American Indian and Alaska Native communities.
- They have the highest rates of new cases and deaths for liver and bile duct cancer of any group.
- They have higher death rates from kidney cancer than any other group.
- They have higher rates of new cervical cancer than several other groups. Hispanic, Latina, and Black women do too.
Liver, kidney, and cervical cancers are key areas for these communities. Ask your provider what screening or prevention fits you.
Why the gaps exist
Like all cancer gaps, these have many causes. NCI points to social determinants of health, the conditions where people are born, live, work, and age. Barriers to care matter too.
Distance can be a challenge. A long trip to screening or treatment can be a barrier. NCI also notes that living in a rural area can shape cancer disparities.
Access barriers, including distance from care, are central to these gaps.
Respecting diversity
It is important to remember that American Indian and Alaska Native peoples are not a single group. They include many nations, languages, and cultures, and cancer patterns can vary among them.
Because of this, general numbers only go so far. Your own risk and screening plan are best set with your provider. They can weigh your history and your local resources. This includes tribal and community health programs.
Care works best when it respects each community and each person.
Steps that can help
Ask your provider which cancer screenings are right for you and when. If travel, cost, or paperwork is a barrier, say so. A patient navigator or social worker may be able to help, and so may tribal and community health programs. If you are facing cancer, it is fair to ask about screening, care, and local resources.

Common questions
What cancer disparities affect American Indian and Alaska Native communities?
NCI data show they have the highest rates of liver and bile duct cancer of any racial or ethnic group. They also have higher kidney cancer death rates than any other group, and higher cervical cancer rates than several other groups.
Why is liver cancer a particular concern?
American Indians and Alaska Natives have the highest incidence and death rates for liver and bile duct cancer, followed by Hispanics and Latinos, then Asians and Pacific Islanders. This makes prevention and early detection especially important for these communities.
Why do these disparities happen?
NCI links cancer disparities to social determinants of health, which are the conditions where people are born, live, work, and age, and to barriers to getting care.
Does where people live matter?
NCI notes that where people live, including rural areas, can affect cancer disparities. Long travel distances to screening or treatment can be a barrier.
Are all Native communities the same?
No. American Indian and Alaska Native peoples include many distinct nations and cultures, and cancer patterns can vary among them. Personal risk and screening are best discussed with your own provider.
What can help reduce these disparities?
Ask your provider which screenings are right for you, and ask about help with barriers such as travel or cost. A patient navigator or social worker can help you reach care.
Questions to ask your doctor
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Last updated: 2026-10-16Next planned review: 2028-07-14
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Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Source checked — This page was written with AI assistance and then compared with the sources listed on it, looking for statements those sources do not back up. That check is not a sentence-by-sentence record and can miss errors. It is not a medical review, and it does not confirm the page is complete or right for your situation.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
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